产品货号：
Z16198
中文名称：
FRMPD2抗体
英文名称：
Anti-FRMPD2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FRMPD2 Antibody |
| 指标别名 | PDZK4,PDZD5C,PDZK5C,PDZK4,FERM and PDZ domain-containing protein 2,PDZ domain-containing protein 4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | FRMPD2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FRMPD2 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FRMPD2.The immunogen is located within amino acids 80 - 130 of FRMPD2. |
| 计算分子量 | 144kDa |
| 成分 | FRMPD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FRMPD2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one,erzin,radixin,moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain.FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL.FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1.Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation,indicating that FRMPD2 plays a major role in tight junction formation.Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion. |
| Uniprot ID | Q68DX3 |
| 基因名全称 | FERM and PDZ domain containing 2 |
| 蛋白名全称 | FERM and PDZ domain containing 2 |
| 推荐稀释比 | FRMPD2 antibody can be used for detection of FRMPD2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in rat samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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